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Figure 12 3.6.4 Metabolic pathway enrichment analysis As shown in Figure 13 , preliminary analysis and found that the main difference pathways between FI group and NC group were Autophagy-other, Autophagy-animal, Glycosylphosphatidyylinositol (GPI)-anchor biosynthesis, Glycerophospholipid metabolism

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Ethanol-induced suppression of SIRT3 and the concomitant increase of another acetylation pathway (i.e., cyclophilin-D acetylation) could be prevented by AMPK activation (Shulga and Pasorino 2010)